It is hard to predict things, especially the future.
  • Niels Bohr


  • @ryneches: by Dec 31, 2015, Illumina reads will be longer than Sanger reads ever were. (> 1kb)
  • @arturgreensward: by Dec 31, 2015, PacBio will be the only thing used to sequence bacterial genomes
  • @pathogenomenick: by Dec 31, 2014, there will be two Nanopore platforms usefully available
  • OH: by Dec 31, 2013, Mick will ask for an embargo on new assemblers
  • @lexnederbragt: 2014-2015, diploid aware assemblers will emerge
  • @pathogenomenick: by end of 2015, graph based variant calling will be default
  • @ryneches: by 2016, computation will be considerably more expensive than sequencing
  • @ctitusbrown: by 2016, the field will have solved the expensive computation problem and > 50% of non-biomedical computational analysis will be a commodity service (although it may not be a particularly good commodity service)

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Questions (and some answers) about sequencing and assembly

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